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Howard Hughes Medical Institute Program

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Phage Hunters Program
Academic Year 2011-2012

Phage Hunters Program Phage Hunters Program Phage Hunters Program Phage Hunters Program
       
Phage Hunters Program Phage Hunters Program    


Our Phage Hunters program consisted of a two-semester laboratory sequence to which we recruited incoming freshmen who would not have been permitted to start the normal General Biology sequence.  Each student recruited to the fall 2011 course, BIO 110, was taking at least one pre-college course to satisfy admission requirements.  This program was supported, in part, by the Howard Hughes Medical Foundation.

In the first semester, in BIO 110, each student collected, isolated and purified a virus from soil samples they collect on campus.  DNA was extracted from each purified virus and was characterized by each student preparing a DNA fingerprint.  Electron micrographs also were taken of each virus.  Samples of each virus were sent to laboratories at the University of Pittsburg for archiving and two were to be fully sequenced.  Each student named and posted data on their newly discovered virus on the Phages DataBase website <phagesdb.org>.

In the second semester, the phage hunter students were enrolled in BIO 111, the first semester of General Biology lecture, and the second semester phage hunters laboratory course (a designated section of the BIO 111 laboratory).  In the laboratory, each student prepared a full research poster on their first semester work and presented the poster at the F.E. Mapp Science Symposium.  We also designed and conducted an experiment to focus on development of experimental design skills.  Annotation of the complete DNA sequences of two viruses was the major focus of this course.  Annotation involved identifying potential genes, choosing a start for each gene, verifying gene calls against national databases, and identifying potential gene functions.  The semester concluded with a presentation of our findings by our students in the Department of Biology Seminar Series.

HHMI International Study Abroad
   
Elijah Martin

Elijah Martin
Major: Biology/French
Hometown: Rockville, MD
Research Mentor: Dr. Alexandra Peister
Research Topic: Using S-SHIP Promoter Expression as a marker to Isolate and Characterize Stem Cell Populations MCF-7 and MCF-10A Cell Lines

Elijah Martin participated in our 2011 study abroad summer program travelling to Lille France, The Pasteur Institute

This was a collaborative effort between the Morehouse College HHMI program and the LSU HHMI program.

 
Elijah Martin

 


 

Genomics Consortium for Active Teaching (GCAT)
This project has begun developing new courses as well as modules for existing STEM courses. HHMI funding will assist in distributing DNA microarrays for courses and modules that consist of hands-on learning at other minority serving institutions involved in the consortium.

GCAT Training at Morehouse College:
July 6-10, 2009