About Brian M. Lawrence, Ph.D.

Education

HARVARD UNIVERSITY, Cambridge, MA
--- A.M./Ph.D., Chemistry (2004)
--- Thesis Title: Toward Colombiasin A
--- Advisor: Eric N. Jacobsen, Sheldon Emery Professor of Chemistry

UNIVERSITY OF CALIFORNIA AT BERKELEY, Berkeley, CA
--- B.S., Chemistry, with honors (1994)

Professional Experience

MOREHOUSE COLLEGE
Department of Chemistry
830 Westview Drive SW, Atlanta, Georgia
--- Associate Professor, Chemistry (Current Appointment),
--- Assistant Professor, Chemistry (2006 to 2015)

GEORGIA INSTITUTE OF TECHNOLOGY
Department of Chemistry and Biochemistry
901 Atlantic Drive, Atlanta, Georgia
--- Visiting Scientist (2008 to 2015)

ARIAD PHARMACEUTICALS, INC.
26 Landsdowne Street, Cambridge, Massachusetts
--- Senior Research Scientist (2004 to 2006)

HARVARD COLLEGE
Kirkland House, 95 Dunster Street, Cambridge, Massachusetts
--- Resident Tutor in Chemistry (1996 to 2003)

Publications

  • Lawrence, B. M.; Crews, D. K. On the Origins of Regioselectivity in the Orthoester Claisen Rearrangment of Bisallylic Alcohols. Tetrahedron Lett., 2015 56, 1297 doi:10.1016/j.tetlet.2014.11.102
  • Appleton, A. L.; Miao, S.; Brombosz, S. M.; Berger, N. J.; Barlow, S.; Marder, S. R.; Lawrence, B. M.; Hardcastle, K. I.; Bunz, U. H. F. Alkynylated Aceno[2,1,3]thiadiazoles. Org. Lett., 2009 11(22), 5222 doi:10.1021/ol902156x
  • Sawyer, T. K.; Shakespeare, W. C.; Wang, Y.; Sundaramoorthi, R.; Huang, W.-S.; Metcalf, C. A., III; Thomas, M.; Lawrence, B. M.; Rozamus, L.; Noehre, J.; Zhu, X.; Narula, S.; Bohacek, R. S.; Weigele, M.; Dalgarno, D. C. Protein phosphorylation and signal transduction modulation: Chemistry perspectives for small-molecule drug discovery. Med. Chem. 2005 1(3), 293 doi:10.2174/1573406053765486
  • Jarvo, E. R.; Lawrence, B. M.; Jacobsen, E. N. Highly Enantio- and Regioselective Quinone Diels-Alder Reactions Catalyzed by a Tridentate (Schiff Base)CrIII Complex. Angew. Chem. Int. Ed. Engl., 2005 44, 6043 doi:10.1002/anie.200502176
  • Boezio, A.; Jarvo, E. R.; Lawrence, B. M.; Jacobsen, E. N. Efficient Total Synthesis of (–)-Colombiasin A and (–)-Elisapterosin B: Application of the Cr-Catalyzed Asymmetric Quinone Diels-Alder Reaction. Angew. Chem. Int. Ed. Engl., 2005 44, 6046 doi: 10.1002/anie.200502178
  • Lawrence, B. M. Toward Colombiasin A. Ph.D. thesis. Harvard University, Cambridge, MA, 2004
  • Rich, R. H.; Lawrence, B. M.; Bartlett, P. A. Synthesis of (–)-2-Chloroshikimic Acid. J. Org. Chem. 1994 59(3), 693 doi: 10.1021/jo00082a038